Search This Blog

COVID-19 Vaccine :
Pfizer and BioNTech Announce Early Positive Data from an Ongoing Phase 1/2 study of mRNA-based Vaccine Candidate Against SARS-CoV-2 
https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-announce-early-positive-data-ongoing-0
mRNA seems to be the shortest path to vaccine.
https://en.wikipedia.org/wiki/Messenger_RNA
https://www.genome.gov/genetics-glossary/messenger-rna
https://fr.wikipedia.org/wiki/Vaccin_%C3%A0_ARN
https://www.nature.com/articles/nrd.2017.243

 
Pandemic is accelerating : 
10M cases
0.5M deaths
Brazil : 60K deaths and counting
India is booming
https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

World / India & South America

The pandemic is accelerating.

+ 150 000 new cases / day (the most in a single day so far).

The world is in a new and dangerous phase.

Many people are understandably fed up with being at home.
Countries are understandably eager to open up their societies and economies.

But the virus is still spreading fast, it’s still deadly, and most people are still susceptible.

We call on all countries and all people to exercise extreme vigilance.

Continue maintaining your distance from others.
Stay home if you feel sick.
Keep covering your nose and mouth when you cough.
Wear a mask when appropriate.
Keep cleaning your hands.

We continue to call on all countries to focus on the basics:
find, isolate, test and care for every case.
Trace and quarantine every contact.

As the pandemic gathers pace, it’s the most vulnerable who will suffer the most.

All countries rich and poor have populations who are vulnerable to a higher risk of severe disease and death.

https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---19-june-2020


https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6

Today good news :
It is also Father's Day
https://www.google.com/doodles/fathers-day-2020-june-21
and the international Music Festival Day ...
https://fetedelamusique.culture.gouv.fr/

US / New York :
More deaths in New York than in France !
https://en.wikipedia.org/wiki/COVID-19_pandemic_in_New_York_(state)
https://en.wikipedia.org/wiki/COVID-19_pandemic_in_New_York_City
https://commons.wikimedia.org/wiki/File:COVID-19_outbreak_New_York_CSA_per_capita_cases_map.svg
https://github.com/ythlev/covid-19
https://www.arcgis.com/home/item.html?id=e34701f45bf6484ca14e0ba2d9e4939f
Bugs in France Maps
https://en.wikipedia.org/wiki/ArcGIS
Correct Data are here :
https://www.santepubliquefrance.fr/content/download/250742/document_file/HDF_PER_COVID19_20200507.pdf 



Countries with NO Lock Down :
https://en.wikipedia.org/wiki/COVID-19_pandemic_lockdowns
+ Sweden :
https://www.forbes.com/sites/alexandrasternlicht/2020/04/30/trump-says-sweden-paying-heavily-for-failure-to-lock-down-as-deaths-toll-rise-over-2500/#5cd61b897ec3
No lockdown here. Swedish high school students—with characteristic caps—celebrate their graduation at a restaurant in Stockholm, Sweden
https://specials-images.forbesimg.com/imageserve/1210995549/960x0.jpg 
https://www.lci.fr/international/video-coronavirus-en-suede-pas-de-confinement-pas-de-desastre-2152992.html
+ Netherlands :
https://www.dutchnews.nl/news/2020/05/easing-the-dutch-coronavirus-rules-what-the-experts-say/
https://www.lefigaro.fr/international/coronavirus-plus-de-1200-morts-et-21-000-cas-aux-pays-bas-20200409
+ Switzerland :
https://www.heidi.news/sante/qu-attendons-nous-en-suisse-et-a-geneve-pour-entrer-en-lock-down-complet
+ Japan :
https://www.ft.com/content/9bac4ad5-22e3-4bcd-b07b-8a248fe44465
+ South Korea :
https://time.com/5830594/south-korea-covid19-coronavirus/
https://www.worldometers.info/coronavirus/#countries
G20 Deaths / 1M population
G20 Ranked per GDP https://en.wikipedia.org/wiki/G20 :
> x100 differences !
United States : 252
China : 3
Japan : 5
Germany : 93
India : 2
United Kingdom : 482
France : 414
Italy : 511
Brazil : 59
Canada : 137
South Korea : 5
Russia : 15
Australia : 4
Mexico : 30
Indonesia : 4
Saudi Arabia : 8
Turkey : 46
Argentina : 7
South Africa : 3
https://edition.cnn.com/2020/05/08/health/germany-south-korea-easing-coronavirus-measures-intl/index.html

Worldwide / Folding@Home
1st ExaFLOP, more than 10 times the performance of the fastest HPC &
faster than the top 500 supercomputers combined. 
https://twitter.com/foldingathome
https://twitter.com/foldingathome/status/1249778379634675712
https://pbs.twimg.com/media/EVgatWWWAAAL6LG?format=png&name=4096x4096
The exaFLOP barrier was first broken in March of 2020 by the Folding@home project, used to fold proteins for medical research.[4][5]
https://en.wikipedia.org/wiki/Exascale_computing
Further use grew from increased awareness and participation in the project from the coronavirus pandemic in 2020.
On March 20, 2020 Folding@home announced via Twitter that it was running with over 470 native petaFLOPS[138], the equivalent of 958 x86 petaFLOPS.[139]
https://twitter.com/drGregBowman/status/1241037866215657472
https://twitter.com/drGregBowman/status/1240408735190847489
By March 25 it reached 768 petaFLOPS, or 1.5 x86 exaFLOPS, making it the first exaFLOP computing system.[140]
https://twitter.com/foldingathome/status/1242918035788365830 
https://en.wikipedia.org/wiki/Folding@home
Apr 28 : 2,621,965 x86 TFLOPS = 2.6 ExaFLOPS
https://stats.foldingathome.org/os
https://www.top500.org/lists/
Rank System Cores Rmax (TFlop/s) Rpeak (TFlop/s) Power (kW)
1 Summit - IBM Power System AC922, IBM POWER9 22C 3.07GHz, NVIDIA Volta GV100, Dual-rail Mellanox EDR Infiniband , IBM
DOE/SC/Oak Ridge National Laboratory
United States
2,414,592 148,600.0 200,794.9 10,096

https://www.top500.org/lists/2019/11/
Mar 25 : 1,554,728 TFLOPS
https://www.anandtech.com/show/15661/folding-at-home-reaches-exascale-1000000000000000000-operations-per-second-for-covid-19
https://jedi.group/
https://www.hpcwire.com/2020/04/22/billion-molecules-against-covid-19-challenge-to-launch-with-massive-supercomputing-support/
http://folding.stanford.edu/
https://foldingathome.org/project-timeline/
https://foldingathome.org/covid19/
https://foldingathome.org/2020/04/17/new-foldinghome-software-with-the-option-to-prioritize-covid-19-projects/
https://foldingathome.org/2020/03/30/covid-19-free-energy-calculations/
https://foldingathome.org/2020/03/15/coronavirus-what-were-doing-and-how-you-can-help-in-simple-terms/
https://stats.foldingathome.org/teams
https://qarnot.com/en/about-us/
https://twitter.com/Qarnot/status/1253581519974793216
Epita : https://stats.foldingathome.org/team/12096
epita-cri : https://stats.foldingathome.org/donor/65367186
France / Sanofi (EURONEXT: SAN) (NASDAQ: SNY)
Tests : 
Sanofi and Luminostics to join forces on developing breakthrough COVID-19 smartphone-based self-testing solution
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-04-16-14-00-00-2017250-en.pdf
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-04-16-14-00-00-2017250-fr.pdf
https://luminostics.com/
Vaccines :
https://www.sanofi.com/fr/media-room/communiques-de-presse/2020/2020-04-24-07-30-00 
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-04-24-07-30-00-2021459-fr.pdf
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/Sanofi-et-GSK-sassocient-dans-une-collaboration-sans-prcdent-pour-lutter-contre-le-COVID19-FR.pdf
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-04-10-07-55-20-2014764-fr.pdf
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-03-27-07-00-00-2007404-fr.pdf
https://www.sanofi.com/-/media/Project/One-Sanofi-Web/Websites/Global/Sanofi-COM/Home/media-room/press-releases/2020/2020-02-18-16-00-00-1986380-fr.pdf

FRANCE / Open Source ICU Ventilator
MakAir
https://makair.life/
https://github.com/makers-for-life/makair/
Medical contacts : 
http://www.itun.nantes.inserm.fr/Team-5/Pierre-Antoine-Gourraud
+ ST / NUCLEO_F411RE
On the MotherBoard
stm32duino
https://github.com/makers-for-life/makair/tree/master/src/software/firmware
https://github.com/makers-for-life/makair
https://github.com/makers-for-life/makair/blob/master/src/electronics/motherboard/schematics/V2/Electrical%20Schematics.pdf
+ PID
https://fr.wikipedia.org/wiki/R%C3%A9gulateur_PID
https://en.wikipedia.org/wiki/PID_controller
SEB
https://www.bfmtv.com/economie/covid-19-seb-va-produire-un-respirateur-artificiel-a-bas-couts-1898929.html
CEA
http://www.cea.fr/presse/Pages/actualites-communiques/sante-sciences-du-vivant/covid19-dispositifs-assistance-respiratoire-urgence-.aspx
Porteurs principaux du projet : Makers For Life, CHU de Nantes, Université de Nantes et CEA
Collectivités, Administrations et Associations : Région Auvergne Rhône-Alpes, Région Pays de Loire, Nantes Métropole, DGE, AID, SFMC
Partenaires industriels : Tronico, Parrot, STMicroelectronics, Diabeloop, Maatel, Groupe Renault, Michelin, Legrand, Groupe SEB, Elpack Pharel
Partenaires académiques et hospitaliers : CHRU Brest, CHU de Grenoble L’école du design, IUT Nantes, Centrale Nantes, Clinatec, Polytech Nantes, Laboratoire LS2N
Partenaires plasturgies : Innovation Plasturgie Composites, Georges Pernoud, Zedes, Seco Industries, Fédération de la Plasturgie et des Composites, DPH International, Moules Soufflage Injection
Partenaires entreprises : Clever Cloud, Crisp, RTSys, Jabby Technologies, SenX, QBMaker, MD101 Consulting, Sleepinnov, Le Palace, Dici Design Renault Sport, Cooprint,  Pierre Pezet, Iliad, Altran, Oxygen Ouest, Le Palace, ASI, Semtech, Farnell, Association Ping, Extia, Aptatio, Safran, HP, Algolinked, Asten Santé, WeData, LVL Medical, Vitalaire
Hommes et Femmes clés : Julien Tanguy, Morgane Soulard, Volodia Lepron, Pierre Papin, Clément Niclot, Cherine Kamel, Quentin Adam, Sandra Roze, Valérian Saliou, Edyta Bourgeais, Vincent Le Cunff, Marc Julien, Gabriel Moneyron, Gautier de Saint Martin Lacaze, David Sferruzza, Emmanuel Feller, Grégory Thibord, Erik Huneker, Cyril Michaud, Baptiste Jamin,Pierre-Antoine Gourraud, Stéphane Bernier, Arthur Dagard, Quentin Bouquin, Maud Plombas, Eliott Vincent.
https://unnews.univ-nantes.fr/le-makair-un-respirateur-artificiel-dedie-au-traitement-du-covid-19-pret-a-entrer-en-essais-cliniques--2635597.kjsp

FRANCE / Makers against COVID-19
At 3:40 : R&D Projects with
ICU Ventilator (MUR) &
Syringe Pump (Electrolab)
A good résumé by Mr. Bidouille of the different actions of the Makers in France (in French)
https://www.youtube.com/watch?v=lnM7UVT2i-o&t=220

Mobile
Bluetooth BLE
Apple and Google partner on COVID-19 contact tracing technology
https://www.blog.google/inside-google/company-announcements/apple-and-google-partner-covid-19-contact-tracing-technology/
https://www.apple.com/newsroom/2020/04/apple-and-google-partner-on-covid-19-contact-tracing-technology/
https://www.blog.google/documents/57/Overview_of_COVID-19_Contact_Tracing_Using_BLE.pdf
https://www.blog.google/documents/58/Contact_Tracing_-_Bluetooth_Specification_v1.1_RYGZbKW.pdf
https://www.blog.google/documents/56/Contact_Tracing_-_Cryptography_Specification.pdf
https://www.blog.google/documents/55/Android_Contact_Tracing_API.pdf
https://worldwide.espacenet.com/publicationDetails/biblio?II=6&ND=3&adjacent=true&locale=en_EP&FT=D&date=20101230&CC=US&NR=2010330903A1&KC=A1#
https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2007063220
https://patentscope.wipo.int/search/en/detail.jsf?docId=US43505818
https://patentscope.wipo.int/search/en/detail.jsf?docId=FR187425572
US / Impact on Economy :
Up to one-third of US jobs may be vulnerable
and more than 80 percent are held by low-income workers.
Up to more than 50M jobs lost ?
https://www.mckinsey.com/industries/public-sector/our-insights/lives-and-livelihoods-assessing-the-near-term-impact-of-covid-19-on-us-workers
https://www.mckinsey.com/~/media/McKinsey/Industries/Public%20Sector/Our%20Insights/Lives%20and%20livelihoods%20Assessing%20the%20near%20term%20impact%20of%20COVID%2019%20on%20US%20workers/Lives-and-livelihoods-Assessing-the-near-term-impact-of-COVID-19-on-US-workers.ashx
https://www.cbia.com/news/economy/hospitality-healthcare-retail-covid-19-jobs-hit/
https://www.marketwatch.com/story/the-us-officially-lost-701000-jobs-in-march-but-in-reality-millions-vanished-2020-04-03?mod=article_inline
https://www.bls.gov/news.release/empsit.nr0.htm?mod=article_inline
https://www.marketwatch.com/story/jobless-claims-leap-record-66-million-at-end-of-march-as-coronavirus-triggers-mass-layoffs-2020-04-02?mod=article_inline

FRANCE / Virus Propagation
First Case Enigma
"Patient Zero" Enigma
https://fr.wikipedia.org/wiki/Patient_z%C3%A9ro
https://www.liberation.fr/france/2020/04/08/covid19-a-bord-du-charles-de-gaulle-l-inconnue-du-patient-zero_1784604
EPITA / COVID-19 :
https://newsroom.ionis-group.com/2020/04/09/les-etudiants-de-lepita-apportent-leur-aide-dans-la-lutte-contre-le-covid-19/

+ Open Source Syringe Pump Project : 
https://covid3d.org/projects/pousse-seringue 
https://covid3d.org/members
https://www.covid3d.org/contact
https://app.jogl.io/project/185
https://www.dagoma3d.com/dagoma-engagee-contre-le-covid-19
https://twitter.com/Dagoma3D/status/1247569928015818755
https://github.com/dagoma3d
https://covid-19.3ie.fr/
https://covid-19.3ie.fr/projet-pousse-seringue.html
https://www.epita.fr/recherche-innovation/equipes/
https://www.epita.fr/recherche-innovation/laboratoires-innovation-3ie/
https://www.nature.com/articles/s41598-019-48815-9
https://github.com/pachterlab/poseidon

+ Open Source ICU Ventilator Project :
https://en.wikipedia.org/wiki/Ventilator
https://www.mur-project.org/
https://github.com/LeClubSandwichStudio/MUR
Ranked #3 WW https://docs.google.com/spreadsheets/u/1/d/e/2PACX-1vTYAfldxoIiO46VAWH1NlhrwFBn9mguqS2bh1spnLEu4AVVN1cj1vaEm6vOp5Z6UnaAbUwd8dslCXdM/pubhtml#
https://www.groupeseb.com/fr/actualites/ensemble-face-au-covid-19

+ Protections :

https://healphi.org/
https://visieresolidaire.org/fr/
https://actu.fr/ile-de-france/coulommiers_77131/coronavirus-coulommiers-propose-soignants-fabriquer-visieres-partir-son-imprimante-3d_32626145.html

+ Folding@Home
https://foldingathome.org/

+ Education :
https://covid19.cristal.je/

https://newsroom.ionis-group.com/2019/09/03/lepita-ajoute-une-composante-sante-a-son-diplome-dingenieur-en-partenariat-avec-doctolib/

Other IONIS Group initiatives :
Sup'BioTech :
https://www.recherche.supbiotech.fr/covid19
https://www.recherche.supbiotech.fr/covid19en
ISG : 
https://planetesolidaire.optigest.fr/

3D Print / Masks
https://www.francetvinfo.fr/sante/maladie/coronavirus/l-hopital-juste-a-cote-demandait-250-masques-alors-j-ai-pris-la-commande-romeo-14-ans-fabrique-des-masques-chez-lui_3906057.html

Open Source / ICU Ventilator / Ranking
PB560
cpap respirator block diagram
https://www.st.com/en/applications/medical-and-healthcare/cpap-and-respirators.html
https://github.com/PubInv/covid19-vent-list
Recently Medtronic open-sourced one of their ventilators for the duration of the pandemic. However, it may not actually be usable for the most ill COVD-19 patients and does not meet the UK standard
https://twitter.com/RobertLeeRead/status/1246115416029749248
https://medium.com/@RobertLeeRead/medtronic-open-source-ventilator-does-not-meet-uks-rapidly-manufactured-ventilator-systems-81947c72a7ac
https://www.medtronic.com/us-en/e/open-files.html
Puritan Bennett(TM) 560 (PB560)
https://techcrunch.com/2020/03/30/medtronic-is-sharing-its-portable-ventilator-design-specifications-and-code-for-free-to-all/
"En France, Puritan Bennett avait pris le contrôle il y a trois ans d'une société spécialisée dans les appareils d'assistance respiratoire à domicile, Sefam."
https://www.lesechos.fr/1997/07/mallinckrodt-achete-nellcor-pour-12-milliards-de-francs-817785
"Créée en 1982 par Pierrick Haan à la sortie de son école d'ingénieurs"
https://www.lesechos.fr/1994/02/sefam-rachete-par-lamericain-puritan-bennett-876714
Sefam, Nancy, France 
http://www.sefam-medical.com/fr/notre-equipe/
https://www.linkedin.com/in/pierrick-haan-224ba8119/
TELECOM ParisTech 1980 (Sortie)
Board is based on ST10F278 (obsolete, replaced by STM32) from ST Microelectronics
ST10F276.h
Produced by Jabil
Source Code is in C.
Comments are in French.

FRANCE / APHP Projects :

Protection :
https://covid3d.org/projet_visiere

ICU Ventilator :
https://covid3d.org/projet_respirateur

Decathlon Mask :
https://covid3d.org/projet_masque_plongee

Syringe Pump :
https://covid3d.org/projet_pousse_seringue

P.S. : Warning Links have changed :
Example :
https://covid3d.org/projects/pousse-seringue
FRANCE / Companies
Corporates Act :

Accor
ADA
Air France
Air Liquide
Airbnb
Airbus
Alibaba
Auchan
AXA
Bacardi
Balenciaga
BNP Paribas
Bolloré Logistics
Bouygues
Bouygues Telecom
Brico Dépôt
Castorama
Chef français Eric Duquenne
CNES (i.e. Centre National d'Etudes Spatiales)
Cooper
Covea
Cristal Union
Dassault
Dassault Aviation
Decathlon
Dior
Faurecia
France Industrie
Free2Move
Fromagerie Maurice
Garnier
Generali France
Givenchy
Grey Goose
Gucci
Guerlain
Hermès
Île-de-France Mobilités
Iliad
Ipsen
JCDecaux
Kering
L'Oréal
La Poste
La Roche-Posay
Lips France
LVMH
Macif
MACSF
Malakoff Humanis
Nestlé
Opel France
Orange
PepsiCo France
Pernod-Ricard
PSA
RATP
Renault
Saint Laurent
Savonnerie Fer à Cheval
Schneider Electric
SNCF
Société Générale
Tereos
Total
Uber
Valeo

https://www.boursorama.com/bourse/actualites/dons-production-adaptee-respirateurs-l-engagement-des-entreprises-face-au-covid-19-3d3e5b5c2bbbd963ae2c71c2e5eab70d?symbol=1rPAI

FRANCE / ICU / R&D
AXA supports Fund 101 to develop Artificial Intelligence algorithms to predict the occurrence of complications in the treatment of the virus.
https://www.axa.com/en/newsroom/news/a-social-responsibility-bolstering-research-and-healthcare
https://www.argusdelassurance.com/les-assureurs/compagnies/coronavirus-axa-s-engage-aupres-des-chercheurs-et-des-professionnels-de-sante.162721
https://www.linkedin.com/company/101fund/about/
Data & AI Algorithms with Boston Consulting Group
https://www.parismatch.com/Actu/Sante/Coronavirus-le-cri-d-alarme-du-professeur-Chiche-1679947
Pr. Jean-Daniel CHICHE, Président Fonds 101, Réanimation Hôpital COCHIN, Paris
https://www.linkedin.com/in/jean-daniel-chiche-29901011/
https://www.youtube.com/watch?v=etomOnwERFg
https://one-o-one.eu/

WORLD : More than 1 Million cases confirmed Worldwide !


https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6
3D Print / Protections
Cleaning & Distribution Procedure (in French) :
https://drive.google.com/file/d/1LU9QeKwA867tXclxlqmaXUsZaVeH-vZp/view?usp=sharing
https://drive.google.com/file/d/1957-FhykRcWufT_jwnJXhMCIk1yhUm94/view?usp=sharing

ApolloBVM Design :
FAQs :
What are the References for the Pressure Sensors ?
Why use 3 Arduino Boards ?
Why use 2 Motors ?

Source:
http://oedk.rice.edu/ApolloBVM-DIY#parts

BOM :
Motors (2x) - 2000 Series Dual Mode Servo (2000-0025-0002)
Arduino (3x) - Arduino Uno (A000066)
Pressure Sensors ... ?!?
20x4 LCD display

Software :
https://github.com/apollobvm/apollobvm
https://github.com/apollobvm/apollobvm/releases (NOT Yet ...)

Parameters :
  • Tidal Volume (TV): 300 - 650 mL (50 mL increments)
  • Respiratory Rate (RR): 5 - 30 BPM (1 BPM increments)
  • I:E Ratio: 1:2, 1:3, 1:4, 1:5

Parameter Range Default
Respiratory Rate (breaths/min) 5-30 12
VT (Tidal volume in cc, set at 6-8 cc/kg of ideal body weight) 300-650 500
I:E (Inspiratory time/Expiratory time per cycle) 1:2 to 1:4 1:3
PEEP (Positive end expiratory pressure in cmH20) 5-20 8
FRANCE / Protections / 3D Print

Files STL :

Visor_frame_EUROPE_80mm_4hole_v2.stl
https://drive.google.com/file/d/1_KwezekbioGYwOJZ0NjdyBxLSscg8mad/view?usp=sharing

There is also :
Visor_frame_EUROPE_80mm_4hole_v1.stl
Visor_frame_EUROPE_ISO838_v3.stl

Source : 
https://www.youmagine.com/designs/protective-visor-by-3dverkstan

https://www.youtube.com/watch?v=tAcXuqAD4Tk
https://www.covid3d.fr/

3D Printer Files :
Protection, Masks / Decathlon adaptators, Door opener, Switch
https://cults3d.com/fr/collections/accessoires-utiles-coronavirus-covid19-imprimes-3d

FRANCE / Cloud
OVH Free offers for COVID19
https://www.ovh.com
https://open-solidarity.com/

USA / Apollo BVM
M.D. & Engineers
http://oedk.rice.edu/apollobvm/
https://www.youtube.com/watch?v=oLQ5bXakWq8
https://engineering.rice.edu/news/student-invention-gives-patients-breath-life

What is the Simplest & Cheapest Ventilator ?



France / 3D Print at APHP :
Tomorrow there should be 60 3D Printers at APHP / COCHIN.

You should download "APHP approved" STL models and find what Hospital need what here : http://covid3d.org/
France / 3D print of Protections
http://3d4care.org/
3D Printer Files (STL)
www.3d4care.com/document/visiere_prusa.stl

UK / Dyson
Dyson built a ventilator in just 10 days using its digital motor technology.
Dyson is planning an initial run of 15,000 units.
https://www.techspot.com/news/84583-dyson-built-ventilator-10-days-using-digital-motor.html
3D Printer Files for Decathlon Masks

Charlotte Valve :
STL : https://drive.google.com/file/d/1rPgX9XPJWmLrjYk-riDuqfvZzsLSq4er/view?usp=sharing
STP : https://drive.google.com/file/d/14hd6T_mXGeKjv3uPzp2KW_jEkEJykRVJ/view?usp=sharing
DWG : https://drive.google.com/file/d/1Pr-NsMCNa79-rJEHSfVXRJWJp0aRjff3/view?usp=sharing

Dave Valve :
STL : https://drive.google.com/file/d/1vc4wDW2Im63astfLFna90XNaHctbmC2R/view?usp=sharing
STP : https://drive.google.com/file/d/18aqRhSmQOIWZHuwqzV_EMl8DtJaUnjJz/view?usp=sharing
DWG : https://drive.google.com/file/d/1usgGyJxlw37niFQayNASHy3LOm82U8qL/view?usp=sharing


The Minimum to know before you make an ICU Ventilator
(in French : La Ventilation Artificielle, Le minimum à savoir pour faire une machine de ventilation par Dr. Dominique DELERUE).
https://drive.google.com/open?id=1THRsDzxGmPD6rmEz7Rzf-t19oazxCF4n

USA / MIT Open Source Ventilator Project :

MIT-based team works on rapid deployment of open-source, low-cost ventilator | MIT News
http://news.mit.edu/2020/ventilator-covid-deployment-open-source-low-cost-0326

The new device fits around an Ambu bag (blue), which hospitals already have on hand in abundance. Designed to be squeezed by hand, instead they are squeezed by mechanical paddles (center) driven by a small motor. This directs air through a tube which is placed in the patient's airway.



A project done a decade ago in the MIT class 2.75 (Medical Device Design)

https://e-vent.mit.edu/wp-content/uploads/2020/03/DMD-2010-MIT-E-Vent.pdf

https://e-vent.mit.edu/

ISRAEL / Ambu-Vent
https://presidentsreport.technion.ac.il/ventilators-for-life/
https://www.youtube.com/watch?v=H23wEDqV1LA


This video can save lives. Please share this link with people working at Hospitals.

COVID-19 How to Use One Ventilator to Save Multiple Lives
https://www.youtube.com/watch?v=uClq978oohY
Saving 4 Patients With Just 1 Ventilator
https://hackaday.com/2020/03/19/saving-4-patients-with-just-1-ventilator/


Open Source Projects :

https://hackaday.com/2020/03/12/ultimate-medical-hackathon-how-fast-can-we-design-and-deploy-an-open-source-ventilator/

https://www.agorize.com/fr/challenges/code-life-challenge





https://www.linkedin.com/posts/dgiluz_its-working-activity-6647896637630894081-FMSc/
https://dgiluz.wordpress.com/2020/03/23/its-working/


https://www.youtube.com/watch?v=w4Csqdxkrfw
+ 3D Printed "CHARLOTTE" Valve (vs. "CHARLOTTE" Valve + "DAVE" Valve + Reservoir vs. "CHARLOTTE" Valve + "DAVE" Valve + Reservoir + Venturi Valve)
PEEP https://en.wikipedia.org/wiki/Positive_end-expiratory_pressure
Venturi Valve https://www.moscorner.com/en/what-are-the-different-types-of-pneumatic-conveying/
+ Bottle of water (vs. PEEP vs. PEEP + Filter)
+ Tubes
https://www.3dprintingmedia.network/isinnova-shares-3d-printed-adapter-to-turn-snorkeling-mask-into-a-non-invasive-ventilator/

Coronavirus, l’azienda bresciana che ha trasformato una maschera da snorkeling in un respiratore
https://www.corriere.it/tecnologia/20_marzo_23/coronavirus-l-azienda-bresciana-che-ha-trasformato-maschera-snorkeling-un-respiratore-cdf7d0e2-6d14-11ea-ba71-0c6303b9bf2d.shtml?refresh_ce-cp

Decathlon
https://www.courrier-picard.fr/id77108/article/2020-03-23/le-masque-de-snorkelling-de-decathlon-comme-masque-de-protection-dans-les
https://france3-regions.francetvinfo.fr/hauts-de-france/pas-calais/coronavirus-seul-train-fret-chine-france-arret-decathlon-potentiellement-touche-1792455.html

https://www.3dprintingmedia.network/forums/topic/charlotte-valve-by-isinnova-for-non-invasive-ventilator/ 
https://www.linkedin.com/in/cristian-fracassi-b155b05b/
https://www.youtube.com/watch?v=e-sKJf74xuw
https://www.youtube.com/watch?v=w4Csqdxkrfw
https://www.youtube.com/watch?v=kpvkHsWz9VM
https://www.linkedin.com/in/filipkober/
https://www.plasticstoday.com/medical/updated-oem-threatens-sue-startup-saved-lives-3d-printing-medical-valves/123431165062652

https://hackaday.com/2020/03/16/3d-printed-parts-keep-respirators-operational-during-covid-19-epidemic/
https://www.3dprintingmedia.network/covid-19-3d-printed-valve-for-reanimation-device/

France :
https://www.mur-project.org/
https://github.com/LeClubSandwichStudio/MUR

USA :
https://hackaday.com/2020/03/18/can-a-cpap-fan-become-a-ventilator/
https://github.com/jcl5m1/ventilator
https://news.ycombinator.com/item?id=22599415
https://www.youtube.com/watch?v=n57u1NvXBgw
https://www.youtube.com/watch?v=oS6GA83nbds

https://hackaday.com/2020/03/22/coronavirus-and-foldinghome-more-on-how-your-computer-helps-medical-research/
https://hackaday.com/2020/03/18/join-team-hackaday-to-crunch-covid-19-through-foldinghome/

https://github.com/GliaX/faceshield

Imagen de un respiradero fabricado con impresoras 3D en la Zona Franca

https://translate.google.com/translate?hl=en&sl=auto&tl=en&u=https%3A%2F%2Fwww.lavanguardia.com%2Fvida%2F20200322%2F4830789695%2Frespirador-3d-coronavirus-consorci-de-la-zona-franca.html
https://www.lavanguardia.com/vida/20200322/4830789695/respirador-3d-coronavirus-consorci-de-la-zona-franca.html


Ventilator Modes

Parameters
https://www.youtube.com/watch?v=iP_jN1qAPtI

AC = ACV = Assist Control Ventilation = 16 breaths / minute

TV = Tidal Volume = 550 mL = 7 mL/kg
https://en.wikipedia.org/wiki/Tidal_volume

FiO2 = Fraction of inspired Oxygen = 50% (between 21% = air ... 50 % = Toxicity
https://en.wikipedia.org/wiki/Oxygen_toxicity)
https://en.wikipedia.org/wiki/Fraction_of_inspired_oxygen

PEP = PEEP = Positive End Expiratory Pressure = 5 cmH2O (between 0 ... 10)
https://en.wikipedia.org/wiki/Positive_end-expiratory_pressure
https://www.youtube.com/watch?v=iP_jN1qAPtI

https://sofia.medicalistes.fr/spip/IMG/pdf/Comment_administrer_l_oxygene_en_ventilation_spontanee_Pr_Levraut_.pdf